Cymbalta / Duloxetine drug interactions
Cymbalta is the brand name of this medicine and its generic name is duloxetine. Cymbalta which is an antidepressant has been classified under the group known as Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs).
Cymbalta affects the chemicals serotonin and norepinephrine in the brain. These chemicals cause depression when they are in an unbalanced state. Cymbalta is useful in treating general anxiety disorder and major depressive disorder.
This medicine also treats the chronic pain disorder known as fibromyalgia and neuropathy pain caused by nerve damage in diabetic patients. There are also other medical used of Cymbalta. Cymbalta can interact with many drugs as discussed below.
Cymbalta should not be taken with thioridazine or a monoamine oxidase inhibitor (MAOI). The substances such as isocarboxazid, phenelzine, selegiline, rasagiline, or tranylcypromine come under the MAOI group.
Still, if you need to take Cymbalta, you should wait at least for fourteen days after discontinuing an MAOI. Likewise, if you need to take an MAOI when you are already on Cymbalta, stop Cymbalta first, wait for at least five days and then start the MAOI medicine. If you are below twenty-four, you may develop suicidal thoughts when you taken an antidepressant.
After starting your treatment with an antidepressant, visit your doctor regularly for a minimum period of twelve weeks if the treatment is going on.
If you experience any new or severe symptom such as behavior or mood changes, panic attacks, anxiety, difficulty sleeping, irritability, agitation, aggressiveness, hyperactivity or restlessness, you should call your doctor immediately.
This also applies if you feel depression, have suicidal thoughts or have a feeling of hurting yourself. Do not drink alcohol when you take Cymbalta. Alcohol taken with Cymbalta may cause damage to your liver.
Taking Cymbalta with narcotic pain medicine, cold or allergy medicine, medicine for seizures or anxiety, and muscle relaxant can increase the sleepiness caused by Cymbalta.
You should therefore inform your doctor if you are already taking any of the above medicines, before starting Cymbalta. Cymbalta can cause side effects that may affect your thinking and also certain functions. Do not drive or operate machinery after taking Cymbalta.
Before taking Cymbalta you should inform your doctor if you are allergic to any drugs.
You should also let your doctor know if you have liver or kidney disease, seizures or epilepsy, blood clotting disorder, glaucoma, bipolar disorder or a history of drug abuse or suicidal thoughts.
A dose adjustment of special tests may be needed for you if you have any of the above conditions, so that you can take Cymbalta safely. Cymbalta comes under FDA pregnancy category C.
Therefore, it may cause harm to the unborn baby and also may cause problems in the new born baby if the mother has taken this medication late in her pregnancy. Duloxetine can get into the breast milk and so, nursing mothers should not take Cymbalta.
When you are already on Cymbalta, consult your physician before taking any medicine for arthritis, pain, fever, or swelling.
Aspirin, naproxen, ibuprofen, indomethacin, diclofenac, nabumetone, etodolac, piroxicam, and similar other medicines should be taken only after consulting your physician.
Taking these medicines with Cymbalta can cause bruise or bleeding easily. You should inform your physician, before taking Cymbalta, if you are taking medicines such as a blood thinner (warfarine), cimetidine, a diuretic, fluvoxamine, linezolid, lithium, tramadol, St. John’s Wort, tryptophan, antibiotics such as ciprofloxacin or enoxacin, frovatriptan, almotriptan, naratriptan, sumatriptan, zolmitriptan, rizatriptan, or, or any other antidepressant such as desipramine, fluoxetine, and paroxetine, among others.
This list of drugs which should not be taken while you are taking Cymbalta is not complete and there are many more drugs that can interact with Cymbalta. T
alk to your physician about all the medications that you are using, including the overn-the-counter medicines. You also should inform your doctor if you are taking any vitamins, herbal products, minerals, and prescriptions by other doctors for you.